Julia Höglund

My main research interest is how genetic variation has shaped evolution, ranging from its implication in animal populations to disease risk in man. During my PhD, I worked with large-scale genomic datasets to investigate the role of common and rare genetic variants in inflammatory traits and diseases, such as asthma and rheumatic diseases. Acquiring a lot of experience in genomic sequence annotation and prediction of mutational deletieriousness, I will focus my post doctoral research toward creating a sequence annotation model that can score variants and quantify mutational load. Besides developing the model, my main goal will be to apply it to current endangered species such as the arctic fox, and later also already extinct species, such as the woolly mammoth. I will work jointly with Dr Mirte Bosse at Wageningen University and Research.